CEAM6 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES17528-50, ES17528-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014],

Alternate Name: Carcinoembryonic antigen-related cell adhesion molecule 6 (Non-specific crossreacting antigen; Normal cross-reacting antigen; CD antigen CD66c)

Source: Rabbit

Applications: IHC; IF; WB

Dilution: IHC-p 1:50-200, WB 1:500-2000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human CEAM6

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 37kD

Human Gene ID: 4680

Human SWISS Prot NO: P40199

Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane. Cell surface. Localized to the apical glycocalyx surface.

Research Use Only