IL-1 Receptor Accessory Protein Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12081-50, MB12081-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9NPH3

Host: Rabbit

Reactivity: Human

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of IL-1RAcP in HL-60, U251, U87-MGLysates using IL-1 Receptor Accessory Protein antibody.

Bioworld Molecular Weight: Calculated MW: 65 kDa; Observed MW: 78 kDa

Specificity: IgG

Alternative Name: IL-1 Receptor Accessory Protein; IL1R3; C3orf13; IL-1RAcP

Immunogen: Recombinant protein of human IL-1RAcP

Conjugate: Unconjugated

Modification: Unmodified