CDK7-IN-1, an analog of YKL-5-124, is a cyclin-dependent kinase 7 (cdk7) inhibitor, with an IC50 of less than 100 nM, extracted from patent WO 2016105528 A2, Compound 215.

Product information

CAS Number: 1957203-02-9

Molecular Weight: 566.05

Formula: C31H28ClN7O2

Chemical Name: (Z)-N-(3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)-3-[(Z)-[(2E)-4-(dimethylamino)-1-hydroxybut-2-en-1-ylidene]amino]benzene-1-carboximidic acid

Smiles: CN(C)C/C=C/C(/O)=N/C1C=C(C=CC=1)/C(/O)=N/C1=CC(=CC=C1)NC1N=C(C(Cl)=CN=1)C1=CNC2=CC=CC=C21

InChiKey: FONRCZUZCHXWBD-VGOFMYFVSA-N

InChi: InChI=1S/C31H28ClN7O2/c1-39(2)15-7-14-28(40)35-21-9-5-8-20(16-21)30(41)36-22-10-6-11-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-13-4-3-12-24(25)27/h3-14,16-19,33H,15H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b14-7+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.